The prion protein (PrP) is best known for its causative role in several incurable neurodegenerative diseases, including Creutzfeldt-Jakob disease (CJD) in humans, bovine spongiform encephalopathy (BSE) in cattle, scrapie in sheep, and chronic wasting disease (CWD) in cervids [1]. Here, PRNP is linked to Creutzfeldt Jacob disease.