NFKB1 and cancer: In conclusion, here we have demonstrated the NF-κB mediated upregulation of TBX15 in cancer cells, identifying two NF-κB functional motifs in the 5’-flanking region of TBX15. This novel finding together with our previous discovery of an antiapoptotic function of TBX15, support the implication of TBX15 in carcinogenesis.