GATA6 and neoplasm: To gain insight into GATA6 function in PDACs, we compared the transcriptome of tumours belonging to the highest and lowest GATA6 expression quartiles in the PDAC meta-dataset (GATA6high and GATA6low, n=27 for each group) and identified 495 genes upregulated or downregulated in GATA6low versus GATA6high with FDR<0.01 (see online supplementary dataset S2).