Extracellular matrix metalloproteinase inducer (EMMPRIN), also known as CD147 (basigin in mice), is a heavily glycosylated type I transmembrane glycoprotein and expressed widely in tumor cells7 and its expression in tumor is usually very high on the surface of various tumors7, 8, 9, 10, 11. The gene discussed is BSG; the disease is neoplasm.