As the result, HSP60 was down-regulated in bronchial adenocarcinoma, vesical transitional cell carcinoma and carcinosarcoma18, 19, 20, 21 whereas the high HSP60 expression was presented in cervical cancer, prostate cancer, breast cancer and GBM22, 23, 24, 25. Here, HSPD1 is linked to prostate carcinoma.