SSNA1 has been initially characterised as one of the main targets of autoantibodies in the context of Sjögren’s syndrome18, a relatively frequent human autoimmune disorder (about 0.5% prevalence in the population), in which the immune system primarily attacks the glands that produce tears and saliva, impairing their ability to secrete these fluids19. This evidence concerns the gene SSNA1 and autoimmune disease.