The result showed that SPANXA was dominantly present in tumor tissues (McNemar test, p = 0.019, Table 1) and the following subtype stratification found that SPANXA expression was upregulated in adenocarcinoma patients (Wilcoxon matched-pairs method, p = 0.028, Supplementary Figure S2B). The gene discussed is SPANXA2; the disease is adenocarcinoma.