However, relatively greater HOTAIR expression (≥ 1.5) was significantly correlated with features also associated with tumour recurrence (e.g., tumour size (P = 0.030), lymphovascular space invasion (LVSI) (P = 0.037), and lymph node (LN) metastasis (P = 0.043)) (Table 1). The gene discussed is HOTAIR; the disease is neoplasm.