Meanwhile, although piR-34736 was found to be underexpressed in breast cancers [18] and lnc-JPH1-7 was also identified in esophageal (ESCCAL-1) [46] and lung (LCAL80) [47] squamous cell carcinomas, their clinical and molecular significance has, up to now, remained uninvestigated. This evidence concerns the gene PIR and squamous cell carcinoma.