Likewise, CD19.CAR CIK cells produced both IFN-γ (27.2%±5.8 with REH; 24.2%±3.5 with primary ALL) and IL-2 (10.1%± 1.2 with REH; 10.6%±1.6 with primary ALL). This evidence concerns the gene IL2 and acute lymphoblastic leukemia.