TP53 and colorectal carcinoma: The IC-50 of ODE was low in p53-wild HCT-116 (33.57± 2.57 μg/mL) and LoVo (12.33 ± 1.51 μg/mL) CRC cells [33–35], but was relatively high in p53-mutant HT-29 (55.56± 3.57μg/mL) and DLD-1 (42.31 ± 3.32μg/mL) cells [33–35].