In the current study, the Hh-related genes, including Bmp4, Gas1, Gli3, Hhip, Ihh, Prkacb, Stk36, Wnt6, Wnt10b, Wnt9a and Wnt11, were dysregulated in our murine model of CCl4-induced liver fibrosis. Here, GLI3 is linked to Hepatic fibrosis.