Here we showed that DbA induced the up-regulation of CAR10 (Figure 2) and EGFR and its downstream signaling molecules (Figure 6J) through the induction of the FoxF2-YB-1 signal cascade (Figure 7H), contributing to lung cancer cell proliferation in vitro and in vivo (Figure 4 to 7). The gene discussed is YBX1; the disease is lung cancer.