We performed a RIP using the lysates of NSCLC cells that did not receive paraformaldehyde treatment, and the results showed that neither CAR10 nor MALAT1 was enriched in the YB-1-antibody-bound complex (Figure 4F), suggesting that YB-1 does not bind to CAR10 after the cells were lysed. This evidence concerns the gene YBX1 and non-small cell lung carcinoma.