Moreover, inhibition of DNMT1 activity with 5-aza-2′-deocycytidine may facilitate the reprogramming of mouse embryonic fibroblasts into pluripotent stem cells [26], and drugs that seem to be inefficient in solid tumors could be applicable to particular subgroups of patients with pancreatic ductal adenocarcinoma [27]. The gene discussed is DNMT1; the disease is pancreatic ductal adenocarcinoma.