Considering mTOR signal pathway controls protein synthesis in different levels by increasing the translation of certain mRNAs, we hypothesize here that the activation of mTOR signal transduction pathway by paracrine action of BM-MSCs after myocardial infarction, will further increase cardiomyocyte protein synthesis and glucose metabolism, and then improve systolic function of heart. Here, MTOR is linked to myocardial infarction.