GSTM1 and systemic inflammatory response syndrome: Two samples with free hemoglobin (Hb) > 0.6 g/L were excluded as hemolytic from further analysis (Supplementary Fig. 1A), leaving 89 samples divided into five groups (Supplementary Fig. 1B): severe sepsis (n = 21); non-severe sepsis (n = 8); severe non-infective SIRS (n = 23); non-severe non-infective SIRS (n = 21); and patients without SIRS (no-SIRS controls, n = 16).