HOXA9 and leukemia: This analysis showed that genes downregulated by CCI-007 in PER-485 cells demonstrated strong enrichment for genes upregulated in MLL-r leukemia (NES = −1.54; FDR:0.107, Figure 5A) as well as for HOXA9/MEIS1 target genes (NES = −1.64; FDR:0.066) (Figure 5B) [70].