Interestingly, this analysis revealed that, within the MLL-r leukemia cell lines, CCI-007 resistant MLL-r leukemia cells had significantly higher baseline expression levels of MEIS1 and BCL2 compared to sensitive cell lines, indicating selective targeting of MLL-r cells with lower baseline MEIS1 and BCL2 expression levels by CCI-007 (Figure 6A). This evidence concerns the gene MEIS1 and leukemia.