The MLL-wt leukemia cells included cell lines harbouring a CALM-AF10 gene fusion (U937 and KP-MO-TS), SET-NUP214 fusion (Loucy) or chromosome 8 trisomy (KG-1), all previously described to be characterised by HOXA9 pathway upregulation [27, 28]. Here, KMT2A is linked to leukemia.