Interestingly, however, morpholino-based modest reduction of TRNT1 levels in zebrafish model recapitulated the vision-selective phenotype, whereas the more severe knock-down also resulted in an eye and heart development abnormalities, reduced touch response and erythrocyte maturation, recapitulating some of the SIFD features. The gene discussed is TRNT1; the disease is congenital sideroblastic anemia-B-cell immunodeficiency-periodic fever-developmental delay syndrome.