We found that 9 lncRNAs (CDKN2B-AS1, EGOT, H19, HOTAIR, LOC285194, RMRP, RNY5, SOX2-OT and SRA1) were significantly modulated in a concordant manner in both end- and non end-stage HF patients (Fig. 2; Additional file 1: Table S5). The gene discussed is SOX2; the disease is hydrops fetalis.