The incidence of hypoglycemia in patients receiving an insulin dose of <29.7 units or ≥29.7 units was 27.5 % (n = 11) or 32.3 % (n = 10), respectively, in the placebo group and 39.5 % (n = 15) or 40.5 % (n = 15), respectively, in the canagliflozin group. Here, INS is linked to Hypoglycemia.