In contrast, N-terminally myristoylated PfRab5b that lacks a C-terminal cysteine residue localizes to the parasite food vacuole and the plasma membrane [27], indicating functional diversification of Rab5 subfamily members in Plasmodium. Apart from this, intracellular malaria parasites secrete hundreds of proteins into the host RBC cytoplasm for which vesicular trafficking is also proposed to be involved. The gene discussed is RAB5A; the disease is malaria.