CX3CR1 and Abnormal retinal morphology: In the retina, the loss of CX3CR1 signaling in retinal disease has been associated with alterations in pathological phenotypes in mouse models of retinal diseases such as diabetic retinopathy (Cardona et al., 2015; Kezic et al., 2013), glaucoma (Wang et al., 2014), uveitis (Dagkalis et al., 2009), oxidative injury (Chen et al., 2013), and light‐induced injury (Sennlaub et al., 2013).