CX3CR1 and retinitis pigmentosa 1: To confirm and elucidate the role of retinal microglia in photoreceptor degeneration(Zhao et al., 2015), we investigated how CX3CR1 deficiency, a key regulator of microglial physiology (Combadiere et al., 2007; Liang et al., 2009), influences microglial involvement and disease progression in the rd10 model for RP.