The fat mass and obesity associated (FTO) gene variant rs9939609 has also been associated with increased risk of NAFLD and the Melanocortin 4 Receptor (MC4R) rs12970134 variant with increased ALT levels, independently of BMI, in children aged 7–18 years old with NAFLD [81]. Here, MC4R is linked to obesity due to melanocortin 4 receptor deficiency.