NFKB1 and colitis: Similar to their data, we found that GC showed beneficial effect on DSS-induced colitis in mice, such as less body weight loss, improved survival rate, weaker pathological damage, and decreased production of proinflammatory cytokines compared to the control group exposed to DSS, and GC treatment also attenuated cytokines production and suppressed NF-κB activation in RAW264.7 cells after LPS stimulation.