LRRK2 and Parkinson disease: These disorders include, among others, Parkinson's disease (PD) with SNCA, PINK1, PARK2, GBA1, and LRRK2 mutations [68–70], amyotrophic lateral sclerosis (ALS) with TDP43 mutation [71], Huntington's disease (HD) with HTT mutation [72], and Spinal muscular atrophy (SMA) with SMN1 mutation [73].