Additionally, circulating CTRP1 levels were significantly increased in both subjects with preDM (352.8 ± 327.9 ng/mL) and T2DM (355.3 ± 341.3 ng/mL), compared with normal subjects (103.7 ± 53.4 ng/mL) on average. Here, C1QTNF1 is linked to type 2 diabetes mellitus.