Accumulating evidence has demonstrated that omentin not only acts as an adipocytokine that participates in energy metabolism but also serves as an anti-inflammatory cytokine involved in inflammatory regulation, and it is associated with chronic inflammatory and autoimmune diseases such as diabetes, atherosclerotic disease, and rheumatoid arthritis [16, 17, 19, 20, 25]. Here, ITLN1 is linked to rheumatoid arthritis.