Univariate Cox proportional hazard regression analysis indicated that FIGO stage (P = 0.002), pelvic lymph node metastasis (P = 0.019), deep cervical stromal invasion (P = 0.028), lymphovascular space invasion (P < 0.001), and PTK6 expression (P = 0.017) were significantly associated with OS of patients with early-stage cervical squamous cell cancer. Here, PTK6 is linked to cervical squamous cell carcinoma.