ATRX and oligodendroglioma: Finally, molecular substratification of tumors according the WHO 2016 revision (i.e., absence of LOH 1p/19q as the defining marker for oligodendrogliomas) confirmed the prognostic role of ATRX (loss: n = 112; median: 1769 days) compared to tumors without ATRX loss (Fig. 3c, n = 118; median: 1127 days, HR = 1.56, 95%CI = 1.14–2.13, p = 0.0046).