UBIAD1 and corneal dystrophy: Exclusion of this family and reanalysis resulted in the expansion of the candidate interval and the identification of pathogenic mutations in the UBIAD1 gene, located outside of the original interval.[20, 21] Therefore, WES was employed to identify the genetic basis of chromosome 10q23-q24 linked corneal dystrophy, with the initial filtering performed for variants identified in the previously linked interval.