COL17A1 and corneal dystrophy: Linkage analysis mapped the dystrophy to an approximately 25 Mbp region on chromosome 10q23-q24 with a maximum multipoint LOD score of 5.5.[8] Examination of the genes mapped to the linked interval on chromosome 10q23-q24 led to the identification of COL17A1 as both a positional and functional candidate, but screening of the gene did not reveal any presumed pathogenic variants.[12] Thus, both the clinical and genetic characterization of chromosome 10q23-q24 linked corneal dystrophy remained ambiguous.