In KSpn-mediated suppression of AAD we identified important suppressive roles for: TLR2 in eosinophil infiltration into the airways (partial) and AHR; TLR4 in eosinophilia of the airways and blood, IL-5 and IL-13 release from splenocytes and AHR, and; MyD88 in airway and blood eosinophilia and AHR (Fig 7). Here, TLR4 is linked to Increased total eosinophil count.