In line with this, Beider et al. [34] observed that the survival and proliferation of CXCR4-expressing tumor cells were supported by the stroma and that this bone marrow stromal cell-induced protection of Burkitt lymphoma cells could be reversed by the CXCR4 antagonist BKT140, increasing rituximab-induced tumor cell death. This evidence concerns the gene CXCR4 and neoplasm.