In thisobservational study, it was determined that for every increase of 1 mmol/L (39mg/dL) in triglyceride-rich cholesterol (remaining), which is mediated bygenetic cause, an increase in risk for coronary artery disease (CAD) was 2.8higher than in controls.17 Themain genes associated with increased levels of triglycerides (as main phenotype)are APOA5, APOC2, APOE, GPD1, GPIHBP1, HNF1A, LMF1, LPL and SLC25A40. The gene discussed is APOE; the disease is coronary artery disorder.