Royo and colleagues performed transcriptomic profiling of urinary EVs obtained from prostate cancer and benign prostate hyperplasia patients using HumanHT-12 v4 Expression BeadChip and found two RNA transcripts, Cadherin 3, type 1 (CDH3) and CKLF-Like MARVEL Transmembrane Domain Containing 3 (CMTM3), exhibited the predicted behavior [17]. The gene discussed is CMTM3; the disease is Familial prostate cancer.