Meanwhile, IUGR tended to decrease gene expressions of TLR-9 (−26%, P = 0.08) and TLR-2 (−22%, P = 0.07), but feeding NT diet significantly increased (+25∼58%, P<0.05) gene expressions of TLR-9, TLR-4 and Claudin-1. Here, CLDN1 is linked to fetal growth restriction.