EGF and nasopharyngeal carcinoma: Keratinocyte-SFM is a complete serum-free medium supplemented with human recombinant Epidermal Growth Factor (rEGF) and Bovine Pituitary Extract (BPE), which has been successfully used to support the growth of primary nasopharyngeal epithelial cells and nasopharyngeal carcinoma cells [21, 22].