EBV-DNA, microRNA signatures, Bmi-1, and the NPC-SVM classifier [28–30] have been reported as valuable predictors in NPC patients [31–33], but it remains difficult to identify uniform criteria among different institutions, and it is also difficult to use as a routine test in clinical practice due to either relatively higher costs or complicated test procedures. The gene discussed is BMI1; the disease is nasopharyngeal carcinoma.