Gene expression meta-analysis identified VDAC1 as a predictor of poor outcome in early stage NSCLC, and knockdown of VDAC1 expression has been shown to inhibit cancer cell proliferation and tumor growth [26, 27], which prompted us to hypothesize that miR-320a may affect NSCLC cell viability through VDAC1. This evidence concerns the gene VDAC1 and cancer.