By evaluating the expression of EpCAM at both RNA and protein levels in 4 normal fresh-frozen ovaries and 96 EOC biopsies (50 primary ovarian carcinomas, 34 metastatic, and 12 recurrent ovarian tumors, respectively), Bellone et al. found that EpCAM was significantly expressed in EOC tissues compared to the normal ovary tissues, and metastatic/recurrent tumours were found to express higher levels of EpCAM than primary ovarian carcinomas. The gene discussed is EPCAM; the disease is neoplasm.