CD44 and neoplasm: Katia et al selected a CD44+/CD24+/EpCAM+/E-cadherin− subpopulation of cells from EOC cells (SKOV-3 and OVCAR-5) using flow cytometry, and found that this small population of cells (less than 1%) has increased colony formation and shorter tumor-free intervals on a mouse s.c xenograft model in vivo after limited dilution, showing initiating tumor cell properties, and is resistant to both doxorubicin and cispation therapies [67].