OPN1SW and hepatocellular carcinoma: The total number of samples for proteomic analysis was 30, which consisted of the following: group A, 10 samples from HCC patients infected with HBV with BCP double mutations; group B, 10 samples from asymptomatic HBsAg carriers with BCP double mutations, and group C, 10 samples from HBsAg-negative individuals (table 1).