HSPD1 and infection: We previously demonstrated that opsonization of H. capsulatum cells with Hsp60-binding MAbs 6B7 (IgG1, protective antibody) and 7B6 (IgG2b, nonprotective antibody) significantly altered their phagocytosis rate and survival within macrophages, as well as modified the course of infection in a murine disease model (9).