TRP120 and Ank200 target genes of important components of the Jak-Stat pathway, e.g., Jak2, Stat1, Stat3, Stat5, and IFNR2, and thus might be involved in regulation of IFN-γ signaling during infection (Zhu et al., 2009; Luo et al., 2011). The gene discussed is IFNG; the disease is infection.