Monocyte chemoattractant protein-1 (MCP-1), also called C-C chemokine ligand 2 (CCL2), one of the ligands for C-C chemokine receptor type 2 (CCR2), has been implicated not only in insulin resistance but also in progressive renal injury, and has been suggested to be a potential marker of renal disease. The gene discussed is CCR2; the disease is kidney disorder.