Feingold (1975) has initially claimed the detrimental effect of Allura Red to childhood behavior more than 30 years ago. Hyperactive is a pattern of behavior that showed substantial individual differences in the general population. Children probably found the above behavior pattern a large degree diagnosed with ADHD (Feingold, 1975; Overmeyer and Taylor, 1999; McCann et al., 2007). Recently, few studies have been published on the issue of Allura Red binding to human serum albumin (HSA) (Wang et al., 2014; Masone and Chanforan, 2015; Wu et al., 2015). The gene discussed is ALB; the disease is attention deficit-hyperactivity disorder.