FPAs, commonly refer to monoclonal, originate from adrenocorticotropic hormone (ACTH) cell adenoma, thyrotropin-stimulating hormone (TSH) cell adenoma, growth hormone (GH) cell adenoma, and prolactin (PRL) cell adenoma, whereas the NFPAs commonly originate from gonadotroph cells (2, 7). The gene discussed is PRL; the disease is adenoma.