A limited list of these markers involved in HCC are SNAIL1, SNAIL2, ZEB1, ZEB2, TWIST1, FOXF1, GATA4, GATA6, CDH1 (E-cadherin), β-catenin, Wnt signaling and CDH2 (n-cadherin) [15]. The gene discussed is TWIST1; the disease is hepatocellular carcinoma.