Moreover, loss of EGFR expression also contributed to inhibition of CRC cell (both HCT116 and SW480 cells) growth (65% or 52% of decrease in HCT116 or SW480 cells) (Figure 4B–4E) and metastasis (63% or 68% of decrease in migration, 76% or 73% of decrease in invasion in HCT116 or SW480 cells) (Figure 4F–4I). This evidence concerns the gene EGFR and colorectal carcinoma.