Approximately 50% of the aforementioned genes that are selectively induced in KRAS-mutant lung adenocarcinomas were also significantly affected by co-occurring mutations in TP53, STK11, or KEAP1. For the most part, co-occurring mutations in STK11 and/or KEAP1 were associated with significantly stronger expression of these genes. The gene discussed is KRAS; the disease is lung adenocarcinoma.