IL-10, as one of the important anti-inflammatory cytokines, was increased at early stage of illness in dengue patients than healthy controls {P = 0.008 (Day 3–5), P = 0.001 (Day 6–7), P = 0.027 (Day 8–10), P = 0.098 (Day 14–17), Fig. 2a}. Here, IL10 is linked to dengue disease.