Analysis of pull-down products by mass spectrometry (MS) (Table 1; Additional file 4: Table S1) revealed that the DEspR-protein interacts with several proteins involved in intracellular trafficking, angiogenesis, and/or cancer: vimentin, Gal-3, Gal-1 and TMED10. The gene discussed is FBXW7-AS1; the disease is cancer.