BMI, body mass index; CRP, C-reactive protein; CVD, cardiovascular disease; GED, graduate equivalency diploma; HDL, high-density lipoprotein; HOMA-IR, homoeostasis model assessment – insulin resistance; JHS, Jackson Heart Study; LDL, low-density lipoprotein; SES, socioeconomic status. The gene discussed is CRP; the disease is Insulin resistance.